In article , drjohn@NOSPAM.hotpotmail.com (Dr
John Watson) wrote:

> *From:* Dr John Watson 
> *Date:* Tue, 29 Apr 2008 13:32:23 +0100
> 
> Noticed at Tue, 29 Apr 2008 03:46:00 -0700: mustaphasiddique 
> informed us:
> 
> > With Cannabis you reach a saturation point where taking any more 
> > in is
> > meaningless. It simply wont have any more effect. This is why it 
> > is so
> > safe with respect to really dangerous drugs like alcohol.
> 
> The reason being that THC attaches to the anandamide receptors. 
> When all
> the receptors are occupied, any further amount of THC won't have a 
> free
> receptor, so it does nothing.
Not /absolutely true/ or how could you explain the two day coma of those who have
carried oil internally and it leaked?
> 
> -- 
> Dr John Watson
> Baker Street
> 
>

Noticed at Tue, 29 Apr 2008 23:13:00 +0100: Claude informed us:

> In article , drjohn@NOSPAM.hotpotmail.com (Dr
> John Watson) wrote:
> 
>> *From:* Dr John Watson 
>> *Date:* Tue, 29 Apr 2008 13:32:23 +0100
>> 
>> Noticed at Tue, 29 Apr 2008 03:46:00 -0700: mustaphasiddique 
>> informed us:
>> 
>> > With Cannabis you reach a saturation point where taking any more 
>> > in is
>> > meaningless. It simply wont have any more effect. This is why it 
>> > is so
>> > safe with respect to really dangerous drugs like alcohol.
>> 
>> The reason being that THC attaches to the anandamide receptors. 
>> When all
>> the receptors are occupied, any further amount of THC won't have a 
>> free
>> receptor, so it does nothing.

> Not /absolutely true/ or how could you explain the two day coma of those who have
> carried oil internally and it leaked?

Because it isn't all absorbed at once. In my scenario, the excess THC
molecules would be available to replace those used up, until they're
broken down.

>> 
>> -- 
>> Dr John Watson
>> Baker Street
>> 
>>
-- 
Dr John Watson
Baker Street

Noticed at Tue, 29 Apr 2008 23:13:00 +0100: Claude informed us:

> Not /absolutely true/ or how could you explain the two day coma of those
> who have carried oil internally and it leaked?

Do you have a link for this, please? It would be useful to me as an
example of the non-toxic nature of cannabis. This leak must be equivalent
to 1,000s of joints-worth of THC etc.

I have also heard (although this sounds apocryphal) that somebody snorted
LSD, thinking it was cocaine, and likewise spent several days in a coma
with no long-term harm. A line of cocaine is around 250mg, a dose of LSD
is 250ug (micrograms). This person ingested 1,000 doses of LSD.

-- 
Dr John Watson
Baker Street